This study challenges current understanding that atypical ductal hyperplasia (ADH), a type of breast tissue abnormality, leads to breast cancer in the same breast while atypical lobular hyperplasia (ALH), another type of breast tissue abnormality, may not be a direct precursor of breast cancer, but may indicate equal risk of breast cancer across both breasts.
“Most have considered ADH a direct precursor to breast cancer, arguing that it requires complete surgical excision while others have maintained that ALH serves as an indicator of heightened and equal risk of breast cancer across both breasts and does not need complete surgical removal,” explained Hartmann. “Moreover, some experts have argued that women with atypia develop ‘better risk’ breast cancers, meaning low-grade cancers with a good prognosis.”
IT IS NOW RECOMMENDED THAT WOMEN HAVE LUMPECTOMIES WITH ADH - or ATYPICAL DUCTAL HYPERPLASIA. Isn't this comparable to having a hysterectomy if you have an abnormal PAP?
Its challenging enough that DCIS has been advanced to "cancer" when it was considered a watch and wait for many years. Now atypia will lead to lumpectomy just as DCIS. This seems as if they aren't making enought money with the current population -- that now they want to advance the surgical intervention in hyperplasia. I don't know what you think ---- but I think this is really pushing the limits.......
ADH, cytologically, architecturally and on a molecular basis, is a low-grade ductal carcinoma in situ (DCIS);[1] however, it has a limited extent, i.e. is present in a very small amount (< 2 mm). ADH is not considered breast cancer,[2] but recognized as a risk for breast cancer. The usual treatment is lumpectomy to exclude the presence of breast cancer
I'd rather have a simple blood test to see if there is a elevation of enzymes present with active cancer -- before I submit to lumpectomy for atypia...
Look for Cancer Profile - American Metabolic Laboratory -- and determine your actual risk.
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